Fatal chlormethiazole poisoning in chronic alcoholics.

chronic alcoholics . chlormethiazole infusion in Cardiac arrest following

Introduction Chlormethiazole is a sedative and hypnotic with marked anti-convulsant properties. It is widely used in the treatment of states characterized by convulsions and agitation, including delirium tremens. Although rarely causing side effects, the drug has been shown to depress the respiratory centre (Lechat, 1966) and toxic interactions with alcohol have been found in animals (Vapaatalo...

Controlled trial of chlormethiazole in treatment of the alcoholic withdrawal phase.

Accidental ingestion of 'Ecstasy' (3,4-methylenedioxymethylamphetamine).

There is no report of the effects of 'Ecstasy' (3,4-methylenedioxymethylamphetamine) poisoning in childhood. The case of a 13 month old boy who ingested one capsule of Ecstasy is reported. Neurological and cardiovascular side effects predominated, which responded well to treatment with a chlormethiazole infusion.

The fatal booze!—triple acid–base disorder in a patient with alcohol intoxication

Patients of chronic alcohol abuse can present with a variety of acid-base disorders and electrolyte disturbances. Lactic acidosis (LA) along with alcoholic ketoacidosis is an infrequent and underappreciated cause of wide anion-gap metabolic acidosis in alcoholic patients. The likelihood of misdiagnosing the condition is high because of the lack of awareness and presence of nonspecific clinical ...

An association between Wernicke's encephalopathy and thyrotoxicosis.

THE SYNDROME bearing Wernicke's name was first documented by Gayet (1875). Wernicke (1881) described three cases, two occurring in chronic alcoholics, the other following sulphuric acid poisoning. Wechsler (1932) appears to be the first person to associate this encephalopathy with a vitamin deficiency. Jolliffe, Wortis & Fein (1941) and Campbell & Russell (1941) have described many cases, the m...